Cutaneous manifestations of systemic diseases
Framing
- Skin findings frequently provide the first visible clue to an underlying systemic disease - endocrine (diabetic dermopathy, hirsutism), rheumatological (dermatomyositis, Raynaud, Behcet), and other systemic processes (angioedema, spider naevi reflecting hepatic disease) each produce characteristic cutaneous signatures
- Recognising these cutaneous signs prompts appropriately directed systemic work-up, making the skin a genuinely diagnostic window into systemic disease rather than an isolated organ to be considered separately
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