HaematologyTier 1Topic overview

Disorders of coagulation or thrombosis

Framing

  • Coagulation disorders span failure of hemostasis (bleeding-prone: thrombophilia's opposite, consumptive coagulopathy in DIC) and excess clot formation (thrombophilia, venous thromboembolism) - both ends require an accurate mechanistic diagnosis before treatment, since anticoagulation is correct for one direction and potentially harmful in the other (e.g. active DIC-related bleeding)
  • Anticoagulant/antiplatelet/antifibrinolytic drug classes are the shared pharmacological toolkit across this whole topic, with agent choice determined by the specific indication

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