Evoked potentials - effect of demyelination (latency vs amplitude)
Core concept
- Evoked potentials measure conduction time and signal size along a sensory pathway (visual, somatosensory, brainstem auditory) after a defined stimulus
- Demyelination -> inc latency (slowed conduction, saltatory conduction lost/impaired) -- the primary abnormality
- Axonal loss -> dec amplitude (fewer functioning fibres contributing to the summed signal) -- a separate abnormality from a different pathology
3 more sections, plus exam facts
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