Hypothalamic–pituitary axis disorders
Framing
- Hypothalamic-pituitary axis disorders reflect either hormone excess (acromegaly - growth hormone, Cushing disease - ACTH) or hormone deficiency (hypopituitarism, affecting one or more anterior pituitary axes) - most commonly arising from a pituitary adenoma (functioning, causing excess; or non-functioning, causing deficiency through mass effect/stalk compression) or other structural/infiltrative pathology
- See for the underlying tonic-inhibition regulatory principle most relevant to prolactin specifically within this axis
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