Medication adherence

Framing

Medication non-adherence is common and multifactorial - patient-related (health literacy, beliefs about medication, psychological factors), regimen-related (complexity, side effects), and system-related (cost, access) factors all contribute, and effective improvement strategies must be matched to the specific barrier identified rather than applying a generic intervention uniformly
Non-adherence should be actively considered whenever a patient's clinical response is unexpectedly poor, before assuming treatment failure and escalating therapy

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