GastroenterologyTier 2Disease (DEADMAN)

Sinusoidal obstruction syndrome

Description

  • Sinusoidal obstruction syndrome (SOS, formerly veno-occlusive disease) - toxic injury to hepatic sinusoidal endothelium causing sinusoidal obstruction, congestion, and centrilobular hepatocyte damage - most commonly a complication of haematopoietic stem cell transplant conditioning regimens

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