Sleep disorders
Framing
- Sleep disorders span disordered breathing during sleep (obstructive sleep apnoea and other sleep-disordered breathing), primary insomnia, and parasomnia/movement disorders (REM sleep behavioural disorder, restless legs syndrome) - each with a distinct mechanism and diagnostic test of choice (polysomnography for sleep-disordered breathing, clinical history-based diagnosis for most insomnia)
- REM sleep behavioural disorder warrants specific attention as a potential early marker of neurodegenerative disease (particularly synucleinopathies - Parkinson disease, dementia with Lewy bodies), often preceding the motor/cognitive diagnosis by years
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