NeurologyTier 1Disease (DEADMAN)

Third, fourth and sixth cranial nerve palsies

Description

The three nerves
SuppliesPalsy: eye positionDiplopia worstHead posture
III oculomotorSR, IR, MR, IO, levator, parasympathetic to sphincter pupillae + ciliaryDown and out, ptosis, +/- dilated pupilAll directions except abductionVariable
IV trochlearSuperior oblique (intorsion, depression in adduction)Hypertropia, extorsionDown and in (reading, stairs)Head tilt away from lesion
VI abducensLateral rectusEsotropia, fails to abductLooking toward the lesion, distanceFace turn toward lesion
  • SO4, LR6, all the rest 3 (superior oblique IV, lateral rectus VI)
Anatomical quirks that get examined
  • IV - only cranial nerve to decussate and to exit dorsally; longest intracranial course -> most vulnerable to closed head injury; bilateral IV palsy after trauma is classic
  • VI - longest intradural course, runs over the petrous ridge -> false localising sign of raised ICP
  • III - pupillomotor fibres run superficially and dorsomedially
    • Compression hits the pupil first; ischaemia (vasa nervorum, core) spares it
    • This single fact drives the whole acute assessment
Parkinson's law of the third nerve
  • Painful + pupil-involving III palsy = posterior communicating artery aneurysm until proven otherwise

6 more sections, plus exam facts

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